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KMID : 0362919910090010103
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1991 Volume.9 No. 1 p.103 ~ p.109
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The Role of Radiotherapy in StageⅠ, Ⅱ Intermediate Grade Non-Hodgkin’s Lymphoma
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Yun Hyong-Geun
Kim Il-Han
Kim Heung-Tae
Ahn Yong-Chan
Kim Jae-Sung
Ha Sung-Whan
Park Charn-Il
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Abstract
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Radiotherapy result of 162 patients with stage Ⅰ, Ⅱ Intermediate Grade Non-Hodgkin’s lymphoma was analyzed to clarify the role and limit of radiotherapy. Of 68 initial failures, 38.2% stageⅠ was 30.0% and 70.0%, respectively with involved field treatment and was 43.8% and 56.2% with extended field treatment, respectively; in stageⅡ, was 16.7% and 83.3%, 41.7% and 58.3% and 40.4% for patients with stage Ⅰ and Ⅱ, respectively. The survival was significantly different by stage. Bulky tumors (≥10 cm) and B symptoms didn’t influence prognosis significantly. The 5 year disease free survival with extended or wide field was better than that with involved field especially in stage Ⅰ.
Overall survival rates for all patients, patients with stageⅠ, and Ⅱ disease were 57.7%, 65.3% and 52.2%, respectively, after survival gain of the salvage chemotherapy was combined. But the overall survival of stageⅠ disease was not better than that of stageⅡ disease. Thus, extended field was required to achieve better disease free survival and relapsed cases might gain with chemotherapy.
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KEYWORD
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Radiotherapy, Non-Hodgkin’s Lymphoma, Intermediate grade, StageⅠ, Ⅱ
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